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Hoag’s Cancer Clinical Trials Are a Game Changer for Orange County

Hoag is bringing the cancer treatments of tomorrow to Orange County today.

Empowered by science, innovative technology and community support, Hoag’s robust cancer clinical trial program targets cancers of all types, many that have progressed on standard treatments with novel approaches and new targeted drugs.

Cell Therapy

Cell therapy, a type of immunotherapy, involves genetically altering immune cells to recognize – and kill – cancer. Hoag is involved in a variety of cell therapy trials, evaluating “natural killer,” or NK cell therapy, which has proven to be beneficial in solid tumors, and will also offer trials using chimeric antigen receptor (CAR) T cell therapies, which involve modifying the patient’s own immune cells and then reinfusing them into the patient.

Intratumoral Injections

Hoag’s renowned oncologist Diana Hanna, M.D., has launched a truly unique clinical trial that involves injecting two immunotherapy drugs directly into cancer tumors. Known as intratumoral injections, this type of treatment increases the body’s immune response against cancer, while causing fewer side effects. This trial will include a series of injections given as an outpatient and will be the first of its kind.

Device Trials

Hoag is involved in a clinical trial to test the effect of electromagnetic pulses on cancer cells. A research device directs electromagnetic pulses to tumors, damaging the tumor’s DNA, making the cancer more susceptible to chemotherapy drugs. The new trial will target the accumulation of fluid within the abdomen produced by ovarian cancer cells. The device, which acts like a wrap around the woman’s abdomen, targets the cancer cell and reduces the amount and the reaccumulation of the ascitic fluid thereby providing significant symptomatic relief.

“What we offer to our patients are early phase trials – brand new molecules, new agents, new targets,” said Burton L. Eisenberg, M.D., Executive Medical Director of the Hoag Family Cancer Institute and the Grace E. Hoag Executive Medical Director Endowed Chair. “Our patients do not have to travel outside of Orange County to get the best and newest treatments for cancer.”

For more information, call 888-284-1761.