Hoag Digestive Health Irvine Hoag Hospital Irvine 16405 Sand Canyon Ave. Suite 280 Irvine, CA 92618 Directions Contact 949-764-8379 Find a Doctor Nearby Home > Hoag Digestive Health Irvine 16405 Sand Canyon Avenue Suite 280 Irvine, CA 92618 949-764-8379 Hours of Operation: 8:00 a.m. to 4:30 p.m., Monday-Friday Closed Saturday & Sunday To schedule an appointment in Irvine, please call 949-764-8379.